What drug causes an interaction with sulfonylureas, resulting in antagonistic action in which a larger dose may be required?

Endocrine, Reproductive, and Cardiovascular Drugs

Complete the following and submit your answers.

·         Chapter 23, page 470, Case Study B- Antidiabetic Agents and page 471, questions 1 through 10.

·         Chapter 25, page 494, questions 1 through 10.

Chapter 23, page 470, Case Study B – Antidiabetic Drugs

1.      The physician starts him on glyburide, a sulfonylurea medication.  He explains to Marcus that sulfonylureas work by:

2.      The physician explains to Marcus that one of the side effects of a sulfonylurea medication is:

3.      Prior to prescribing the medication, the physician reviews Marcus’s medical history.  This is because sulfonylureas must be used with extreme caution in individual’s who:

4.      The physician cautions Marcus to call him prior to taking any other medication because of possible interactions.  Which drug can potentiate the hypoglycemic effect of a sulfonylurea?

5.      What drug causes an interaction with sulfonylureas, resulting in antagonistic action in which a larger dose may be required?

Antidiabetic Agents and page 471, questions 1 through 10.

1.      Glucophage – Oral antidiabetic agent

2.      prednisone – Corticosteroid

3.      Humulin R – Insulin: short acting

4.      Synthroid – Thyroid agent

5.      Avandia – Oral antidiabetic agent

6.      Tapazole – Antithyroid

7.      Isophane – Insulin: intermediate acting

8.      Prandin – Oral antidiabetic agent

9.      Lantus – Insulin: long acting

10.  Humalog – Insulin: rapid acting

Chapter 25, page 494 (actually pg. 541), questions 1 through 10

1.      isosorbide – Angina

2.      Zetia – Elevated cholesterol

3.      Lovenox – Pulmonary emboli

4.      Cardizem – Hypertension

5.      Zocor – Elevated cholesterol

6.      Plavix – Stroke prevention (platelet inhibitor)

7.      Crestor – Elevated cholesterol

8.      hydralazine – Hypertension

9.      quinidine – Cardiac arrhythmia

10.  procainamide – Cardiac arrhythmia

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